The latest issue of the Clinical Medicine & Research journal was released Tuesday, December 21. Clinical Medicine & Research is an indexed, peer-reviewed, medical research journal owned and published by Marshfield Clinic Health System, and edited within Marshfield Clinic Research Institute.

The December issue features original research articles discussing aspects of the COVID-19 pandemic, potential prognostic markers for prostate cancer, multidisciplinary rehabilitation program for chronic low back pain, and spondyloarthritis in a child. Also included in the issue are the 2021 annual indexes for subjects, authors, and peer reviewers.

Peer-reviewed original articles in this edition include:

“COVID-19 CHA2DS2-VASc Score: Is It Time to Refine?” by Joshua K. Salabei, MD, PhD

“COVID-19: Highlighting Health Disparities in the Los Angeles Latinx Community” by Ernesto Casillas Jr., MD; Gloria Wu, MD; Stefano Iantorno, MD, PhD; Weihuang Vivian Ning, MD; Joon Choi, MD; Patrick Chan, MD; and May M. Lee, MD

“From Epidemic to Pandemic: Comparing Hospital Staff Emotional Experience Between MERS and COVID-19” by Imran Khalid, MD; Maryam Imran, MBBS; Manahil Imran, MBBS; Muhammad Ali Akhtar, MBBS; Saifullah Khan, MBBS; Khadija Amanullah, MBBS’ and Tabindeh Jabeen Khalid, MD

“Effect of Cholorquine and Hydroxycholorquine on Cytokine Release Syndrome in Patients with COVID-19” by Bilal Ahmad, FCPS; Naeem ul Hassan, FCPS; Bismillah Sehar, MCPS; Falak Zeb, PhD; Dur e Nayab, MCPS; and Fuad Ahmad Siddiqui, FCPS

“Immunohistochemical Evaluation of PARP and Caspase-3 as Prognostic Markers in Prostate Carcinomas” by Victoria Acar; Fabio Leite Couto Fernandez; Fabio Fabian Buscariolo; Adriana Alonso Novais; Roseli Aparecida Matheus Pereira, NP; and Debora Aparecida Pires de Campos Zuccari, PhD

“An Integrated Multidisciplinary Rehabilitation Program Experienced by Patients with Chronic Low Back Pain” by Julie Bøgdal, MHS, OT; Anne Mette Schmidt, PhD, MHS, PT; Kirsten Østergaard Nielsen, RN; and Charlotte Handberg, PhD, MPH, RN

“Torticollis as a Sole Presentation of Spondyloarthritis in a 4-year-old Child” by Nirzar Samir Parikh, MD; Nicholas McClellan, DO; Monica Koehn, MD; and Suhas Ganguli, MD

About the journal

Clinical Medicine & Research debuted in 2003 continuing the Health System’s long history of publishing scholarly journals that dates back to the first half of the 1900s. With an international reach, Clinical Medicine & Research is indexed in major U.S. and international databases of scientific information including Index Medicus/MEDLINE, PubMed Central, EMBASE, Scopus, Emerging Sources Citation Index and many more.

It is one of only a few medical research journals owned and published by private health systems and also included in the U.S. National Library of Medicine's prestigious Index Medicus/MEDLINE database. Other health systems with such indexed journals include Mayo Clinic Health System, Cleveland Clinic, Texas Heart Institute and Menninger Clinic.

Accepted articles are published online at prior to appearing in a formal issue of the journal. The site is accessed more than 20,000 times per month and has more than 100,000 full-text article views or downloads per year.

To submit an article, visit All submitted articles are peer-reviewed first by the executive editorial team. If selected during editorial review, articles are also peer-reviewed by external subject-matter experts. To reach the executive editorial team, email

Members of the executive editorial team include Adedayo Onitilo, M.D., Ph.D., editor-in-chief; Sherry Salzman Scott, M.S., senior editor; Jamiu O. Busari, M.D., Ph.D., associate editor from Horacio Oduber Hospital in Oranjestad, Aruba; and Rohit Sharma, M.D., FACS, associate editor. Members of the editorial advisory board from Marshfield Clinic Health System include Kelley Anderson, M.D.; Jessica Engel, D.N.P.; Steven Taylor, M.D.; and Richard Dart, M.D., editor emeriti.

Photo: The front cover of Clinical Medicine & Research features an artist rendering of a pandemic.

Image credits ANDRZEJ WOJCICKI/Science Source (Unique ID: SS22566314). Image and text copyright © 2021 Science Source/Photo Researchers, Inc. All rights reserved.