• Sarah CJ Jorgensen Pharm.D., Ph.D.

  • Associate Research Scientist


    • MCRI - MCRI-Clin Epidem and Pop Hlth
    • 1000 North Oak Ave. ML2 Marshfield, WI 54449

Education

2024:
PhD, University of Toronto, Toronto, ON, Canada
2019:
MPH, Wayne State University, Detroit, MI
2014:
PharmD, University of Florida, Gainesville, FL
2009:
BPharm, University of British Columbia, Vancouver, BC, Canada
2005:
BS, Mathematics , University of British Columbia, Vancouver, BC, Canada

Work Experience

2024 to Present:
Associate Research Scientist, Marshfield Clinic Research Institute, Marshfield, WI
2023 to 2024:
Postdoctoral Fellow, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada
2023 to 2024:
Postdoctoral Fellow, Ottawa Hospital Research Institute, Ottawa, ON, Canada
2019 to 2021:
Antimicrobial Stewardship Pharmacist, Mount Sinai Hospital, Toronto, ON, Canada
2017 to 2019:
Postdoctoral Fellow, Anti-Infective Research Laboratory, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI
2016 to 2017:
PGY2 Infectious Diseases Pharmacy Resident, University of Southern California/Huntington Hospital, Los Angeles, CA
2016 to 2017:
Adjunct Assistant Professor of Pharmacy Practice, College of Pharmacy, University of Southern California, Los Angeles, CA
2015 to 2016:
PGY1 Pharmacy Practice Resident, Tallahassee Memorial Hospital, Tallahassee, FL
2009 to 2015:
Clinical Pharmacist, Cowichan District Hospital, Vancouver Island Health, Duncan, BC, Canada
2009 to 2011:
Pharmacist, Shoppers Drugmart, Duncan, BC, Canada

Statement

Dr. Jorgensen is an infectious disease epidemiologist and Associate Research Scientist in the Center for Clinical Epidemiology and Population Health at the Marshfield Clinic Research Institute with primary research interests in perinatal epidemiology, vaccine safety and effectiveness, multidrug resistant bacterial infections, antimicrobial stewardship, and antimicrobial pharmacokinetics and pharmacodynamics.

A complete list of Dr. Jorgensen's publications can be found at:
https://www.ncbi.nlm.nih.gov/myncbi/sarah.jorgensen.2/bibliography/public/

Research Interests

Maternal immunization and infant health outhcomes
Pediatric viral respiratory infections
Antimicrobial stewardship
Multidrug resistant bacterial infections
Antimicrobial pharmacokinetics/pharmacodynamics
Research methods

Select Publications

  • Jorgensen, SCJ, Drover, SSM, Fell, DB, Austin, PC, D'Souza, R, Guttmann, A,...Kwong, JC. Association between maternal mRNA covid-19 vaccination in early pregnancy and major congenital anomalies in offspring: population based cohort study with sibling matched analysis. BMJ Medicine. 2024 September 16;3(1):e000743. doi: doi.org/10.1136/bmjmed-2023-000743.
  • Jorgensen SCJ, Brown K, Clarke AE, Schwartz KL, Maxwell C, Daneman N,...MacFadden DR. The Effect of COVID-19 Vaccination on Outpatient Antibiotic Prescribing in Older Adults: A Self-Controlled Risk-Interval Study. Clin Infect Dis. 2024 August 16;79(2):375-381. doi: 10.1093/cid/ciae182. PMCID: PMC11327793.
    PubMed ID: 38700036
  • Jorgensen, SCJ, Hernandez, A, Buchan, SA, Fitzpatrick, T, Guttmann, A, Morris, SK, Kwong, JC. Burden of Illness Associated with Respiratory Syncytial Virus, Influenza, and COVID-19 in Infants and Young Children in Ontario, Canada, 2018-2023: a Population-Based Canadian Immunization Research Network (CIRN) Study. Open Forum Infectious Diseases. 2024 November;33(11):e70012. doi: 10.1093/ofid/ofae601. PMCID: PMC11521330.
    PubMed ID: 39474449
  • Jorgensen SCJ, Drover SSM, Fell DB, Austin PC, D'Souza R, Guttmann A,...Kwong JC. Newborn and Early Infant Outcomes Following Maternal COVID-19 Vaccination During Pregnancy. JAMA Pediatr. 2023 December 1;177(12):1314-1323. doi: 10.1001/jamapediatrics.2023.4499. PMCID: PMC10594175.
    PubMed ID: 37870875
  • Jorgensen SCJ, Hernandez A, Fell DB, Austin PC, D'Souza R, Guttmann A, Kwong JC. Estimated Effectiveness of Postpartum Maternal Messenger RNA COVID-19 Vaccination Against Delta and Omicron SARS-CoV-2 Infection and Hospitalization in Infants Younger Than 6 Months. JAMA Pediatr. 177(4):427-430. doi: 10.1001/jamapediatrics.2022.6134. PMCID: PMC9972229.
    PubMed ID: 36848130
  • Jorgensen SCJ, Hernandez A, Fell DB, Austin PC, D'Souza R, Guttmann A,...Kwong JC. Maternal mRNA covid-19 vaccination during pregnancy and delta or omicron infection or hospital admission in infants: test negative design study. BMJ. 380:e074035. doi: 10.1136/bmj-2022-074035. PMCID: PMC9903336.
    PubMed ID: 36754426
  • Jorgensen SCJ. Nirsevimab: review of pharmacology, antiviral activity and emerging clinical experience for respiratory syncytial virus infection in infants. J Antimicrob Chemother. 78(5):1143-1149. doi: 10.1093/jac/dkad076.
    PubMed ID: 36922390
  • Jorgensen, SCJ, Miljanic, S, Tabbara, N, Somanader, D, Leung, F, De Castro, C,...Burry, L. Inclusion of pregnant and breastfeeding women in nonobstetrical randomized controlled trials. Am J Obstet Gynecol MFM. 2022 November;4(6):100700. doi: 10.1016/j.ajogmf.2022.100700.
    PubMed ID: 35914736
  • Jorgensen SCJ, Burry L, Tabbara N. Role of maternal COVID-19 vaccination in providing immunological protection to the newborn. Pharmacotherapy. 2022 January;42(1):58-70. doi: 10.1002/phar.2649.
    PubMed ID: 34816467
  • Jorgensen SCJ, Dersch-Mills D, Timberlake K, Stewart JJ, Gin A, Dresser LD, Dalton BR. AUCs and 123s: a critical appraisal of vancomycin therapeutic drug monitoring in paediatrics. J Antimicrob Chemother. 2021 August 12;76(9):2237-2251. doi: 10.1093/jac/dkab048.
    PubMed ID: 33675656
  • Jorgensen SCJ, Stewart JJ, Dalton BR. The case for 'conservative pharmacotherapy'. J Antimicrob Chemother. 76(7):1658-1660. doi: 10.1093/jac/dkab011.
    PubMed ID: 33523228
  • Jorgensen SCJ, Spellberg B, Shorr AF, Wright WF. Should Therapeutic Drug Monitoring Based on the Vancomycin Area Under the Concentration-Time Curve Be Standard for Serious Methicillin-Resistant Staphylococcus aureus Infections?-No. Clin Infect Dis. 72(9):1502-1506. doi: 10.1093/cid/ciaa1743.
    PubMed ID: 33740050
  • Jorgensen SCJ, Zasowski EJ, Trinh TD, Lagnf AM, Bhatia S, Sabagha N,...Rybak MJ. Daptomycin Plus ß-Lactam Combination Therapy for Methicillin-resistant Staphylococcus aureus Bloodstream Infections: A Retrospective, Comparative Cohort Study. Clin Infect Dis. 71(1):1-10. doi: 10.1093/cid/ciz746.
    PubMed ID: 31404468
  • Jorgensen SCJ, Trinh TD, Zasowski EJ, Lagnf AM, Bhatia S, Melvin SM,...Rybak MJ. A Multicenter Evaluation of Vancomycin-Associated Acute Kidney Injury in Hospitalized Patients with Acute Bacterial Skin and Skin Structure Infections. Infect Dis Ther. 2020 March;9(1):89-106. doi: 10.1007/s40121-019-00278-1. PMCID: PMC7054514.
    PubMed ID: 31983021
  • Jorgensen SCJ, Trinh TD, Zasowski EJ, Lagnf AM, Simon SP, Bhatia S,...Rybak MJ. Real-World Experience with Ceftolozane-Tazobactam for Multidrug-Resistant Gram-Negative Bacterial Infections. Antimicrob Agents Chemother. 2020 March 24;64(4). doi: 10.1128/AAC.02291-19. PMCID: PMC7179316.
    PubMed ID: 31932379
  • Jorgensen SCJ, Trinh TD, Zasowski EJ, Lagnf AM, Bhatia S, Melvin SM,...Rybak MJ. Real-World Experience With Ceftazidime-Avibactam for Multidrug-Resistant Gram-Negative Bacterial Infections. Open Forum Infect Dis. 2019 December 6;6(12):ofz522. doi: 10.1093/ofid/ofz522. PMCID: PMC6934163.
    PubMed ID: 31890725