• Huong McLean PhD, MPH

  • Research Scientist

    • Center for Clinical Epidemiology & Population Health
    • 1000 North Oak Ave. ML2 Marshfield, WI 54449


PhD, Epidemiology, University of Washington, Seattle, WA
MPH, Epidemiology, University of Minnesota, Minneapolis, MN
BA, Chemistry, College of Saint Benedict, Saint Joseph, MN

Work Experience

2002 to 2004:
Research Fellow, National Immunization Program, Centers for Disease Control and Prevention, Associations of Schools of Public Health, Atlanta, GA
2004 to 2008:
Pre-doctoral Research Associate, Department of Epidemiology, Virology Research Clinic, University of Washington, Seattle, WA
2008 to 2012:
Epidemiologist, Division of Viral Diseases, National Center for Immunizations and Respiratory Diseases, Centers for Disease Control and Prevention (CDC), Atlanta, GA
2012 to Present:
Research Scientist, Marshfield Clinic Research Institute, Marshfield, WI


Dr. McLean is an epidemiologist with focus on infectious diseases and vaccine effectiveness, immunogenicity, safety, promotion, and policy. The majority of her research is on influenza, addressing issues relating to prior vaccination history and vaccine effectiveness, both clinically and immunologically. More recently, her research has expanded to include assesment of SARS-CoV-2 transmission in households and COVID-19 incidence in a community cohort. Her research also includes promoting adolescent vaccinations and examining long-term immunogencity of measles, mumps, rubella (MMR) vaccine.

From 2008-2012, Dr. McLean worked in the Division of Viral Diseases at CDC. She was involved in multiple studies and outbreak investigations for vaccine preventable diseases, served as a WHO consultant on polio eradication in Kenya, and served as the CDC secretariat for the Advisory Committee on Immunization Practices (ACIP) work group on measles, mumps, and rubella vaccine.

Research Interests

-Vaccine effectiveness, immunogencity, safety, policy, and promotion
-Measles, mumps, rubella (MMR)
-Human papillomavirus (HPV)
-COVID-19 and SARS-CoV-2
-Infectious diseases
-Longitudinal cohorts

Select Publications

  • McLean HQ, King JP, Talley P, Flannery B, Spencer S, Levine MZ,...Belongia EA. Effect of Previous-Season Influenza Vaccination on Serologic Response in Children During 3 Seasons, 2013-2014 Through 2015-2016. J Pediatric Infect Dis Soc. 2020 April 30; 9(2):173-180.
    PubMed ID: 30759228
  • McLean HQ, Hanson KE, Foster AD, Olson SC, Kemble SK, Belongia EA. Serious outcomes of medically attended, laboratory-confirmed influenza illness among school-aged children with and without asthma, 2007-2018. Influenza Other Respir Viruses.. 2020 March; 14(2):173-181.
    PubMed ID: 31944583
  • McLean HQ, Belongia EA. Influenza Vaccine Effectiveness: New Insights and Challenges. [published online ahead of print 2020 January 27]. Cold Spring Harb Perspect Med.
    PubMed ID: 31988202
  • Scallan Walter EJ, McLean HQ, Griffin PM. Hospital Discharge Data Underascertain Enteric Bacterial Infections Among Children. [published online ahead of print 2020 February 24]. Foodborne Pathog Dis.
    PubMed ID: 32091947
  • Belongia EA, Levine MZ, Olaiya O, Gross FL, King JP, McLean HQ, Flannery B. Clinical trial to assess immunogenicity of high-dose, adjuvanted, and recombinant influenza vaccines against cell-grown A(H3N2) viruses in adults 65 to 74 years, 2017-2018. [published online ahead of print 2020 March 4]. VACCINE.
    PubMed ID: 32145994
  • Arevalo P, McLean HQ, Belongia EA, Cobey S. Earliest infections predict the age distribution of seasonal influenza A cases. [published online ahead of print 2020 July 7]. Elife. 9
    PubMed ID: 32633233
  • Marin M, Fiebelkorn AP, Bi D, Coleman LA, Routh J, Curns AT, McLean HQ. Adverse Events among Young Adults following a Third Dose of Measles-Mumps-Rubella Vaccine. [published online ahead of print 2020 August 7]. Clin Infect Dis.
    PubMed ID: 32766827
  • Grijalva CG, Rolfes MA, McLean HQ, Hanson KE, Belongia EA, Halasa NB,...Talbot HK. Transmission of SARS-COV-2 Infections in Households - Tennessee and Wisconsin, April-September 2020. MMWR Morb Mortal Wkly Rep. 2020 November 6; 69(44):1631-1634. doi: 10.15585/mmwr.mm6944e1.
    PubMed ID: 33151916
  • Belongia EA, McLean HQ. Influenza Vaccine Effectiveness: Defining the H3N2 Problem. Clin Infect Dis. 2019 October 30; 69(10):1817-1823.
    PubMed ID: 31102401
  • Hanson KE, McLean HQ, Belongia EA, Stokley S, McNeil MM, Gee J, VanWormer JJ. Sociodemographic and clinical correlates of human papillomavirus vaccine attitudes and receipt among Wisconsin adolescents. Papillomavirus Res. 2019 December; 8 :100168. PMCID: PMC6556618.
    PubMed ID: 31136831
  • McLean HQ, Orenstein WA. Protecting Young Infants From Measles. PEDIATRICS. 2019 December 1; 144(6)
    PubMed ID: 31753912
  • Seagle EE, Bednarczyk RA, Hill T, Fiebelkorn AP, Hickman CJ, Icenogle JP,...McLean HQ [including Belongia EA.] Measles, mumps, and rubella antibody patterns of persistence and rate of decline following the second dose of the MMR vaccine. VACCINE. 2018 February 1; 36(6):818-826.
    PubMed ID: 29317117
  • King JP, McLean HQ, Meece JK, Levine MZ, Spencer SM, Flannery B, Belongia EA. Vaccine failure and serologic response to live attenuated and inactivated influenza vaccines in children during the 2013-2014 season. VACCINE. 2018 February 21; 36(9):1214-1219.
    PubMed ID: 29395525
  • King JP, McLean HQ, Belongia EA. Validation of Self-Reported Influenza Vaccination in the Current and Prior Season. Influenza Other Respir Viruses.. 2018 November; 12(6):808-813.
    PubMed ID: 30028081
  • McLean HQ, Fiebelkorn AP, Ogee-Nwankwo A, Hao L, Coleman LA, Adebayo A, Icenogle JP. Rubella virus neutralizing antibody response after a third dose of measles-mumps-rubella vaccine in young adults. VACCINE. 2018 September 11; 36(38):5732-5737.
    PubMed ID: 30107992
  • Frost HM, McLean HQ, Chow BDW. Variability in Antibiotic Prescribing for Upper Respiratory Illnesses by Provider Specialty. J Pediatr. 2018 December; 203 :76-85.
    PubMed ID: 30195553
  • McLean HQ, Caspard H, Griffin MR, Gaglani M, Peters TR, Poehling KA,...Belongia EA. Association of Prior Vaccination With Influenza Vaccine Effectiveness in Children Receiving Live Attenuated or Inactivated Vaccine. JAMA Netw Open. 2018 October 5; 1(6):e183742.
    PubMed ID: 30646262
  • Scallan E, Griffin PM, McLean HQ, Mahon BE. Hospitalisations due to bacterial gastroenteritis: A comparison of surveillance and hospital discharge data. Epidemiol Infect.. 2018 June; 146(8):954-960.
    PubMed ID: 29655383
  • Barnes KL, VanWormer JJ, Stokley S, Vickers ER, McLean HQ, Belongia EA, Bendixsen CG. Determinants of human papillomavirus vaccine attitudes: an interview of Wisconsin parents. BMC Public Health.. 2018 June 15; 18(1):746.
    PubMed ID: 29907115
  • McLean HQ, Peterson SH, King JP, Meece JK, Belongia EA. (2017 May). School absenteeism among school-aged children with medically attended acute viral respiratory illness during three influenza seasons, 2012-2013 through 2014-2015. Influenza Other Respi Viruses. 11(3):220-229.
    PubMed ID: 27885805
  • Belongia EA, Skowronski DM, McLean HQ, Chambers C, Sundaram ME, De Serres G. (2017 July). Repeated annual influenza vaccination and vaccine effectiveness: review of evidence. Expert Rev Vaccines. 16(7):1-14.
    PubMed ID: 28562111
  • McLean HQ, VanWormer JJ, Chow BDW, Birchmeier B, Vickers E, DeVries E,...Belongia EA. (2017 August). Improving Human Papillomavirus Vaccine Use in an Integrated Health System: Impact of a Provider and Staff Intervention. J Adolesc Health. 61(2):252-258.
    PubMed ID: 28462786
  • McLean HQ, Caspard H, Griffin MR, Poehling KA, Gaglani M, Belongia EA,...Ambrose CS. (2017 May 9). Effectiveness of live attenuated influenza vaccine and inactivated influenza vaccine in children during the 2014-2015 season. VACCINE. 35(20):2685-2693.
    PubMed ID: 28408121
  • Van Wormer JJ, King JP, Gajewski A, McLean HQ, Belongia EA. (2017 Dec). Influenza and Workplace Productivity Loss in Working Adults. J Occup Environ Med. 59(12):1135-1139.
    PubMed ID: 28759481
  • VanWormer JJ, Bendixsen CG, Vickers ER, Stokley S, McNeil MM, Gee J,...McLean HQ [including Belongia EA.] Association between parent attitudes and receipt of human papillomavirus vaccine in adolescents. BMC Public Health.. 2017 October 2; 17(1):766.
    PubMed ID: 28969653
  • Belongia EA, Simpson MD, King JP, Sundaram ME, Kelley NS, Osterholm MT, McLean HQ. (2016 August). Variable influenza vaccine effectiveness by subtype: a systematic review and meta-analysis of test-negative design studies. Lancet Infect Dis. 16(8):942-951.
    PubMed ID: 27061888
  • McLean HQ, Chow BD, VanWormer JJ, King JP, Belongia EA. (2016 October 15). Effect of Statin Use on Influenza Vaccine Effectiveness. J Infect Dis. 214(8):1150-1158.
    PubMed ID: 27471318
  • McLean HQ, Thompson MG, Sundaram ME, Kieke BA, Gaglani M, Murthy K,...Belongia EA [including Meece JK.] (2015 May). Influenza Vaccine Effectiveness in the United States During 2012-13: Variable Protection by Age and Virus Type. JOURNAL OF INFECTIOUS DISEASES. 211(10):1529-40.
    PubMed ID: 25406334
  • McLean HQ, Thompson MG, Sundaram ME, Meece JK, McClure DL, Friedrich T, Belongia EA. (2014 November). Impact of Repeated Vaccination on Vaccine Effectiveness Against Influenza A(H3N2) and B During 8 Seasons. Clin Infect Dis.. 59(10):1375-85.
    PubMed ID: 25270645
  • Kutty P, McLean HQ, Lawler J, Schulte C, Hudson J, Blog D, Wallace G. (2014 February). Risk Factors for Transmission of Mumps in a Highly Vaccinated Population in Orange County, New York, 2009-2010. PEDIATRIC INFECTIOUS DISEASE JOURNAL. 33(2):121-5.
    PubMed ID: 23995590
  • McLean HQ, Meece JK, Belongia EA. (2014 January). Influenza vaccination and risk of hospitalization among adults with laboratory confirmed influenza illness. VACCINE. 32(4):453-7.
    PubMed ID: 24291201
  • McLean HQ, Fiebelkorn AParker, Temte JL, wallace GS. (2013 June). Prevention of Measles, Rubella, Congenital Rubella Syndrome, and Mumps, 2013: Summary Recommendations of the Advisory Committee on Immunization Practices (ACIP). MMWR Recomm Rep.. 62(RR-04):1-34.
    PubMed ID: 23760231
  • Marin M, Nguyen HQ, Langidrik J, Edwards R, Briand K, Papania M,...LeBaron CW. (2006 February). Measles transmission and vaccine effectiveness during a large outbreak on a densely populated island: implications for vaccination policy. CLINICAL INFECTIOUS DISEASES. 42(3):315-9.
    PubMed ID: 16392073
  • Nguyen HQ, Jumaan AO, Seward J. (2005 February). Decline in mortality due to varicella after implementation of varicella vaccination in the United States. NEW ENGLAND JOURNAL OF MEDICINE. 352(5):450-8.
    PubMed ID: 15689583
  • Marin M, Nguyen HQ, Keen J, Jumaan AO, Mellen P, Hayes E,...Seward J. (2005 April). Importance of catch-up vaccination: experience from a varicella outbreak, Maine, 2002-2003. PEDIATRICS. 115(4):900-5.
    PubMed ID: 15805362