• John Mayer Ph.D.

  • Research Programmer/Analyst Senior


    • MCRI - MCRI-Res Computing and Analyt
    • 1000 North Oak Ave. ML9 Marshfield, WI 54449

Education

2015 to 2017:
MS, Data Science, University of Wisconsin - Stevens Point, Stevens Point, WI
1995 to 2004:
PhD, Scientific Computing, University of Southern Mississippi, Hattiesburg, MN
1990 to 1993:
MS, Physics, Minnesota State University-Mankato, Mankato, MN
1985 to 1990:
BS, Astronomy, Minnesota State University-Mankato, Mankato, MN

Work Experience

2012 to Present:
Research Programmer/Analyst Sr., Marshfield Clinic , Marshfield, WI
2002 to 2013:
Lecturer, University 0f Wisconsin - Marathon, Wausau, WI
2000 to 2012:
Programmer/Analyst Sr., Marshfield Clinic, Marshfield, WI

Research Interests

Genomic association studies, machine learning (as it applies to disease prediction), numeric modelling of physical systems. In a previous life, stellar evolution and nucleosynthesis in stars.

Select Publications

  • Mayer J, Kitchner T, Ye Z, Zhou Z, He M, Schrodi SJ, Hebbring SJ. (2014 December). Use of an electronic medical record to create the marshfield clinic twin/multiple birth cohort. Genet Epidemiol. 38(8):692-8.
    PubMed ID: 25250975
  • Ye Z, Mayer JG, Ivacic LC, Zhou Z, He M, Schrodi SJ,...Hebbring S [including Brilliant MH.] (2015 April). Phenome-wide association studies (PheWASs) for functional variants. Eur J Hum Genet. 23(4):523-9.
    PubMed ID: 25074467
  • Hebbring SJ, Rastegar-Mojarad M, Ye Z, Mayer J, Jacobson C, Lin S. (2015 June 15). Application of clinical text data for phenome-wide association studies (PheWASs). BIOINFORMATICS. 31(12):1981-7.
    PubMed ID: 25657332
  • Mosley JD, Witte JS, Larkin EK, Bastarache L, Shaffer CM, Karnes JH,...Denny JC [including Hebbring SJ, Brilliant MH, Mayer J, Ye Z.] (2016 April 25). Identifying genetically driven clinical phenotypes using linear mixed models. Nat Commun. 7 :11433.
    PubMed ID: 27109359
  • Liu J, Ye Z, Mayer JG, Hoch BA, Green C, Rolak L,...Hebbring SJ [including Cold C, Brilliant MH.] (2016 October). Phenome-wide association study maps new diseases to the human major histocompatibility complex region. J Med Genet. 53(10):681-9.
    PubMed ID: 27287392
  • Karnes JH, Bastarache L, Shaffer CM, Gaudieri S, Xu Y, Glazer AM,...Denny JC [including Ye Z, Mayer JG, Brilliant MH, Hebbring SJ.] (2017 May 10). Phenome-wide scanning identifies multiple diseases and disease severity phenotypes associated with HLA variants. Sci Transl Med. 9(389)
    PubMed ID: 28490672
  • Tafti AP, Badger J, LaRose E, Shirzadi E, Mahnke M, Mayer J,...Peissig PL [including Ye Z.] (2017 Nov). Adverse Drug event Discovery using Biomedical Literature: a Big Data Neural Network Adventure. JMIR Med Inform.
  • Ahmad P. Tafti, Ehsun Behravesh, Mehdi Assefi, Eric LaRose, Jonathan Badger, John Mayer,...Peggy Peissig. (2017 Dec). bigNN: An open-source big data toolkit focused on biomedical sentence classification. 2017 IEEE International Conference on Big Data (Big Data).
  • Huang X, Elston RC, Rosa GJ, Mayer J, Ye Z, Kitchner T,...Hebbring SJ [including Brilliant MH.] Applying Family Analyses to Electronic Health Records to Facilitate Genetic Research. BIOINFORMATICS. 2018 February 15; 34(4):635-642. doi: doi: 10.1093/bioinformatics/btx569. PMCID: PMC5860602.
    PubMed ID: 28968884
  • Badger J, LaRose E, Mayer J, Bashiri F, Page D, Peissig P. Machine learning for phenotyping opioid overdose events. J Biomed Inform. 2019 June; 94 :103185. PMCID: PMC6622451.
    PubMed ID: 31028874
  • Hansen KE, Johnson MG, Carter TC, Mayer J, Keuler NS, Blank RD. The -839(A/C) Polymorphism in the ECE1 Isoform b Promoter Associates With Osteoporosis and Fractures. J Endocr Soc. 2019 November 1;2019 Jul 15(3(11)):2041-2050. doi: 10.1210/js.2019-00057 . PMCID: PMC6795020.
    PubMed ID: 31637345
  • Huang X, Tatonetti N, LaRow K, Delgoffe, B, Mayer, J, Page D, Hebbring, SJ. E-Pedigrees: a large-scale automatic family pedigree prediction application. BIOINFORMATICS. 2021 November;2021 June 4(btab):419. doi: 10.1093/bioinformatics/btab419 .
    PubMed ID: 34086863
  • Allaire P, He J, Mayer J, Moat L, Gerstenberger P, Wilhorn R,...Hebbring S. Genetic and clinical determinants of telomere length. HGG Adv. 2023 April;4(3):100201. doi: 10.1016/j.xhgg.2023.100201. PMCID: PMC10199259.
    PubMed ID: 37216007
  • Elsayed NS, Valenzuela RK, Kitchner T, Le T, Mayer J, Tang ZZ,...Shukla SK [including Aston P.] Genetic risk score in multiple sclerosis is associated with unique gut microbiome. Sci Rep. 2023 September 27; 13(1):16269. doi: 10.1038/s41598-023-43217-4. PMCID: PMC10533555.
    PubMed ID: 37758833
  • Ye Z, Mayer J, Leary EJ, Kitchner T, Dart RA, Brilliant MH, Hebbring SJ. Estimating the efficacy of pharmacogenomics over a lifetime. Front Med (Lausanne). 2023 October 31;10:1006743. doi: 10.3389/fmed.2023.1006743. PMCID: PMC10645151.
    PubMed ID: 38020121
  • Smith AJ, Patterson BW, Pulia MS, Mayer J, Schwei RJ, Nagarajan R,...Boutilier JJ. Multisite evaluation of prediction models for emergency department crowding before and during the COVID-19 pandemic. J Am Med Inform Assoc. 2023 January 18;30(2):292-300. doi: 10.1093/jamia/ocac214. PMCID: PMC9620348.
    PubMed ID: 36308445
  • Sathipati, SY, Jeong, S, Sharma, P, Mayer, J, Sharma, R, Ho, S, Hebbring, S. Exploring prognostic implications of miRNA signatures and telomere maintenance genes in kidney cancer. Molecular Therapy: Oncology. 2024 December 19;32(4):200874. doi: 10.1016/j.omton.2024.200874.