• Michael Caldwell MD, PhD, FACS

  • Physician - Surgical Wound Care/Hyperbaric


    • Wound Healing Program
    • 1000 North Oak Ave. 3D Marshfield, WI 54449

Education


1980 to 1982:
Surgical, Chief Resident, 1981-1982, Hospital of the University of Pennsylvania, Philadelphia
1980 to 1982:
Clinical Nutrition, Hospital of the University of Pennsylvania, Philadelphia
1980:
PhD, Physiology, Vanderbilt University, Nashville
1972 to 1976:
Clinical Nutrition, Vanderbilt University, Nashville
1971 to 1972:
Neonatal, Medical University of South Carolina, Charleston
1969 to 1971:
Surgical, Medical University of South Carolina, Charleston
1968 to 1969:
Surgical, Medical University of South Carolina, Charleston
1968:
MD, Medical University of South Carolina, Charleston
1964:
BS, Chemistry, University of South Carolina, Columbia

Work Experience


2001 to Present:
General Surgery, Active Status, Ministry St. Joseph's Hospital, Marshfield
2000 to Present:
Director, Wound Healing Program, Marshfield Clinic, Marshfield
2000 to Present:
General Surgery, Marshfield Clinic, Marshfield
2000 to 2006:
Founder/Principal Investigator, Marshfield Clinic's Personalized Medicine Research Project, Marshfield Clinic, Marshfield
2000 to 2004:
Director of Medical Research, Marshfield Clinic Research Foundation, Marshfield
2000 to 2004:
Member, Wisconsin Technology Council, Appointed by Governor Tommy Thompson
2000 to 2001:
General Surgery, Associate Status, Ministry St. Joseph's Hospital, Marshfield
1992 to 2000:
Graduate Faculty, Surgery, University of Minnesota, Minneapolis
1991 to 2000:
Lecturer, Depts of Surgery and Microbiology, University of Minnesota, Minneapolis
1990 to 2000:
General Surgery, Fairview University Hospital System, Minneapolis
1990 to 2000:
General Surgery, Fairview Hospital, Riverside
1990 to 2000:
General Surgery, Unity Hospital, Fridley
1990 to 2000:
General Surgery, Mercy Hospital, Coon Rapids
1990 to 2000:
Director, Center for Wound Healing and Reparative Medicine, University of Minnesota, Minneapolis
1990 to 2000:
Professor of Surgery and Biochemistry, University of Minnesota, Minneapolis
1992 to 1993:
Course Leader, Nutrition, Dept of Biochemistry, University of Minnesota Medical School, Minneapolis
1988 to 1990:
Acting Surgeon-in-Chief, Rhode Island Hospital, Providence
1987 to 1990:
Professor of Surgery, Brown University, Providence
1986 to 1990:
Surgeon-in-Charge, Division of Surgical Research, Rhode Island Hospital, Providence
1983 to 1990:
Preceptor for Brown University Medical Students, Rhode Island Hospital, Providence
1983 to 1990:
Course Leader, BioMed 364 (Nutrition), Brown University, Providence
1983 to 1990:
Lecturer, Pathology Classes, Brown University, Providence
1982 to 1990:
General Surgery, Rhode Island Hospital, Providence
1982 to 1990:
Director, Nutritional Support Service, Rhode Island Hospital, Providence
1982 to 1990:
Director, Surgical Metabolism Laboratory, Rhode Island Hospital, Providence
1982 to 1987:
Associate Professor of Surgery, Brown University, Providence
1981 to 1982:
Instructor, Dept of Surgery, Hospital of the University of Pennsylvania, Philadelphia
1979 to 1980:
Lecturer, Dept of Nutritional Science, University of California, Berkeley
1977 to 1980:
Chief, Nutritional Support Service, Letterman Army Institute of Research, San Francisco
1976 to 1980:
Lieutentant Colonel, US Army Medical Corps
1976 to 1978:
Chief, Division of Surgical Metabolism, Letterman Army Institute of Research, San Francisco
1972 to 1976:
Clinical Coordinator, Vanderbilt Clinical Nutrition Service, Nashville

Board Certifications


1985 to Present:
Fellow, American College of Surgeons
1999 to Present:
Diplomate, American Board of Surgery, 1985, recertified
2000 to Present:
Diplomate, American Board of Clinical Nutrition (1984), Recertified
2001 to Present:
Physician Nutrition Specialist, American Board of Physician Nutrition Specialists

Honors & Awards


1963:
Pi Mu Epsilon, University of South Carolina Chapter
1983:
Excellence in Teaching Award from Surgical Residents, Rhode Island Hospital

Professional Societies


1972 to 1976:
International Society of Parenteral Nutrition
1982 to 1990:
Rhode Island Medical Society
1982 to 1990:
Providence Medical Association
1984 to 1990:
Diabetes and Endocrine Society of Rhode Island, Inc.
1989 to 1990:
RI Chapter, American College of Surgeons/Providence Surgical Society
1984 to 1992:
American Federation for Clinical Research
1978 to 1994:
American Society for Clinical Nutrition
1991 to 2000:
Minnesota Chapter, American College of Surgeons
1991 to 2000:
Minneapolis Surgical Society
1991 to 2000:
Minnesota Surgical Society
1997 to 2000:
Minnesota Vascular Society
1997 to 2002:
Central Surgical Association
1975 to Present:
American Society for Parenteral and Enteral Nutrition
1978 to Present:
American Society for Nutritional Sciences (formerly American Institute of Nutrition)
1982 to Present:
Shock Society
1982 to Present:
Ravdin-Rhoads Surgical Society
1983 to Present:
American Medical Association
1984 to Present:
Association for Academic Surgery
1984 to Present:
Fellow, American Board of Nutrition
1984 to Present:
Fellow, American College of Nutrition
1984 to Present:
American Association for the Advancement of Science
1984 to Present:
New York Academy of Science
1985 to Present:
Society of University Surgeons
1986 to Present:
New England Surgical Society
1987 to Present:
Society for Surgery of the Alimentary Tract
1987 to Present:
Surgical Biology Club II
1988 to Present:
The Wound Healing Society
1989 to Present:
Fellow, American College of Surgeons
1989 to Present:
American Physiological Society
1991 to Present:
Society for Physical Regulation in Biology and Medicine (known as Bioelectrical Repair and Growth Society from 1991-1994)
1993 to Present:
American Surgical Association
1993 to Present:
European Tissue Repair Society
1995 to Present:
Society for Leukoyte Biology

Committees


1975 to 1976:
Organizing Committee, American Society for Parenteral and Enteral Nutrition (ASPEN), Member
1976 to 1981:
Executive Council, American Society for Parenteral and Enteral Nutrition (ASPEN), Member
1977 to 1981:
Journal of Parenteral and Enteral Nutrition, Founder and Editor-in-Chief
1982 to 1983:
Total Parenteral and Enteral Nutrition Committee, Rhode Island Hospital, Chair
1983 to 1985:
House of Delegates, Rhode Island Medical Society, Delegate
1981 to 1986:
Journal of Parenteral and Enteral Nutrition, Associate Editor
1983 to 1986:
Long Range Planning Subcommittee, Brown, University, Member
1983 to 1986:
Operations Committees, VA Cooperative Study, "A Randomized Clinical Trial of TPN in Malnourished Surgical Patients," #221, Washington, DC, Member
1984 to 1986:
MD/PhD Curriculum, Brown University, Member
1984 to 1986:
Pre-Clinical Subcommittee of the MD/PhD Curriculum Committee, Brown University, Member
1985 to 1986:
National Board of Nutritional Support Certification Committee, American Society for Parenteral and Enteral Nutrition (ASPEN), Member
1985 to 1986:
Standards Committee Chair, American Society for Parenteral and Enteral Nutrition, Member
1986 to 1986:
Digestive Tract and Liver Market Focus Group, Rhode Island Hospital, Member
1986 to 1986:
Special Task Force, Recruitment for Dept of Medicine Chair, Rhode Island Hospital, Member
1986 to 1987:
Chair, Subcommittee on JCAHO Standards, Committee on Clinical Practice Issues, American Society of Clinical Nutrition, Member
1985 to 1988:
Board Member, Oley Foundation, Member
1985 to 1989:
Search Committee for Cellular Immunologist, Dept of Pathology, & Vice Chair, Dept of Surgery, Rhode Island Hospital, Member
1986 to 1989:
Board of Directors, American Board of Nutrition, Member
1986 to 1989:
Finances and Fund Raising Committee, American Board of Nutrition, Member
1986 to 1989:
Credentials Committee, American Board of Nutrition, Member
1987 to 1989:
Search for Dept of Orthopedics and Rehabilitation Chair, Rhode Island Hospital, Member
1988 to 1989:
Capital Campaign Steering Committee, Rhode Island Hospital, Member
1988 to 1989:
Secretary/Treasurer, American Board of Nutrition, Member
1982 to 1990:
Department of Surgery, Rhode Island Hospital, Executive Committee
1982 to 1990:
Full-Time Faculty Committee, Department of Surgery, Brown University, Member
1983 to 1990:
MD Curriculum Committee, Brown University, Member
1983 to 1990:
Nutrition Committee, Miriam Hospital / Rhode Island, Member
1984 to 1990:
Rhode Island Hospital Surgery Foundation, Inc., Board of Trustees, Member
1984 to 1990:
Health Services Committee, American Red Cross, Greater Rhode Island Chapter, Member
1984 to 1990:
Pediatric Parenteral Nutrition Committee, Rhode Island Hospital, Member
1984 to 1990:
Medical Dietetics, Rhode Island Hospital, Director
1984 to 1990:
Dietetic Internship Advisory Committee, Rhode Island Hospital, Member
1984 to 1990:
Pension Committee, Rhode Island Hospital Surgery Foundation, Inc., Member
1985 to 1990:
Home Nutrition Committee, Rhode Island Hospital, Member
1987 to 1990:
Graduate Council, Brown University, Member
1987 to 1990:
Research Steering Committee, Rhode Island Hospital, Member
1988 to 1990:
Department Coordinating Committee, Department of Surgery, Rhode Island Hospital, Member
1988 to 1990:
Intellectual Property Committee, Rhode Island Hospital, Member
1988 to 1990:
Administrative Executive Committee, Department of Surgery, Rhode Island Hospital, Member
1988 to 1990:
Operating Room Management Committee, Department of Surgery, Rhode Island Hospital, Member
1988 to 1990:
Surgical Coordinating Committee, Department of Surgery, Rhode Island Hospital, Member
1988 to 1990:
Organizing Committee, The Wound Healing Society, Member
1989 to 1990:
Rhode Island State Board of Dietetics, Member
1989 to 1990:
Search Committee, Surgeon-in-Chief, Rhode Island Hospital, Chairman, Dept of Surgery
1986 to 1992:
American Journal of Clinical Nutrition, Editorial Board Member
1991 to 1992:
Wound Healing Resource Utilization Task Force Clinical Subcommittee, University of Minnesota Hospitals and Clinics, Member
1991 to 1992:
Biomedical Ethics Education Subcommittee, University of Minnesota Hospitals and Clinics, Member
1991 to 1994:
Membership Committee Chair, The Wound Healing Society, Member
1993 to 1994:
Board of Directors, American Board of Nutrition, Member
1990 to 1995:
Board of Directors, The Wound Healing Society, Member
1993 to 1995:
Institute for Basic and Applied Research in Surgery, Dept of Surgery, University of Minnesota, Secretary
1994 to 1995:
Research Process and Reporting Task Force, Dept of Surgery, University of Minnesota, Member
1994 to 1995:
Hemostasis Subcommittee of the Pharmacy and Therapeutics Committee, University of Minnesota, Member
1994 to 1995:
Local Arrangements Chair, Wound Healing Society 1995 Annual Meeting, Minneapolis, Member
1995 to 1995:
Departmental Research Council, Dept of Surgery, University of Minnesota, Chair
1994 to 1996:
Health Sciences Policy and Review, Graduate School of the University of Minnesota, Member
1995 to 1996:
Faculty Organization and Relationship Task Force, University of Minnesota, Member
1995 to 1996:
Faculty Organization and Relationship Task Force, University of Minnesota, Critical Issues Subgroup
1996 to 1996:
Research Training Review Subcommittee, National Institutes of Health, Member
1996 to 1997:
Steering Committee, Minnesota Vascular Center, Member
1996 to 1997:
Marketing Subcommittee, Minnesota Vascular Center, University of Minnesota, Member
1997 to 1997:
Workshop on NIGMS-Sponsored Postdoctoral Research Training in Trauma and Burn Injury, National Institutes of Health, Member
1995 to 1999:
Minnesota Vascular Disease Center Planning and Development, Member
1996 to 1999:
Vascular Care, University of Minnesota Hospital and Clinics, Member
1998 to 1999:
Minnesota Medical Association Public Health and Preventive Medicine, Member
1980 to 2000:
Journal of Clinical Investigation, Ad Hoc Reviewer
1985 to 2000:
Site Visit and Special Review Committee, National Institutes of Health, Member
1990 to 2000:
Journal of Immunology, Ad Hoc Reviewer
1992 to 2000:
Wound Repair and Regeneration, Editorial Board Member
2003:
Workshop on the Proposed American Family Study for the National Institutes of Health, Baltimore, MD, Member
2000 to 2003:
Research Committee, Marshfield Clinic Research Foundation, Chair
2000 to 2004:
Marshfield Clinic Research Foundation Board of Trustees, Ex-Officio Member
2003 to 2004:
Research Committee, Marshfield Clinic Research Foundation, Member
2005:
Concensus Conference on Wound Healing Guidelines, Pressure and Venous Stasis Ulcers, Wound Healing Society, NIH Campus, Washington, DC, Member
2006:
Concensus Conference on Wound Healing Guidelines, Pressure and Venous Stasis Ulcers, Wound Healing Society, NIH Campus, Washington, DC, Member
2006:
NIH-PGRN Retreat, Chicago, IL, Member
2006:
OPASI Roadmap Meeting NIH, Consultant
2006:
NIGMS Council, National Institutes of Health, Ad Hoc Member
2006:
NHLBI Advisory Group on Genotype-Guided Trial of Warfarin Therapy, Member
2006:
Review Panel NIH/Fogarty International Collaborative Trauma and Injury Research Training Program Awards, Member
2006:
Founded the International Warfarin Pharmacogenetic Consortium, Member
2005 to 2006:
Resident Research Committee, Marshfield Clinic Research Foundation, Chair
2007:
Advisory Committee to FDA on Development of the Sentinel Network, Member
2007:
Advisory Panel to NIGMS Regarding Furture Programmatic Development, Member
2007:
NIH/SAT Study Section, Ad Hoc Member
2008:
Journal of Thrombosis and Haemostasis, Ad Hoc Reviewer
2008:
Advisory Committee for Pharmaceutical Science and Clinical Pharmacology, Office of Clinical Pharmacology, Federal Drug Administration, Member
2008:
Pharmacogenetics Subgroup, Personalized Health Care Initiative Workgroup of the American Health Information Community (AHIC), Offic of the Secretary of the Department of Health and Human Services, Member
2001 to Present:
Clinical Medicine and Research, Editorial Board Member
2002 to Present:
Surgery Residency Committee, Marshfield Clinic/St. Joseph's Hospital Joint Residency Program, Member
2002 to Present:
Marshfield Clinic Board of Directors, Member
2006 to Present:
The Belted Galloway Society of the United States, Executive Council

Select Publications


  • Caldwell MD, Cargill R. (1964). Photochemical cyclization of acrylic esters. South Carolina Academy of Science Bulletin. 26 :38.
  • Caldwell MD, Jonsson JT, Otherson HB. (1972 November). Essential fatty acid deficiency in an infant receiving prolonged parenteral alimentation. J Pediatr. 81(5):894-898.
    PubMed ID: 4628753
  • O'Neill JA, Meng HC, Caldwell MD, Otten A. (1974 December). Variations in intravenous nutrition in the management of catabolic states in infants and children. J Pediatr Surg. 9(6):889-897.
    PubMed ID: 4214913
  • Meng HC, Caldwell MD, Sandstead HH. (1976). Total parenteral nutrition in patients with cancer. Clin Res. 24 :A502.
  • Meng HC, Caldwell MD, Sandstead HH. (1976). Total parenteral nutrition in patients with cancer. Am J Clin Nutr. 29 :481.
  • Nichoalds GE, Green HL, Caldwell MD. (1976). Vitamin requirements in patients receiving total parenteral nutrition. Acta Chir Scand. 466 :12-13.
    PubMed ID: 828389
  • O'Neill JA, Meng HC, Caldwell MD, Stahlman MT. (1976 December). Metabolic evaluation of a synthetic amino acid mixture for parenteral nutrition in infants and children. J Pediatr Surg. 11(6):979-985.
    PubMed ID: 826618
  • O'Neill JA, Caldwell MD, Meng HC, Otten A, Stahlman MT. (1976). Use of a 10% l-amino acid solution with glucose in pediatric parenteral nutrition. Acta Chir Scand Suppl. 466 :106-107.
    PubMed ID: 828382
  • Caldwell MD, Exton JH, Lacy WW. (1977). Effect of glucocorticoids in substrate utilization by muscle. Fed Proc. 36 :527.
  • Nichoalds GE, Meng HC, Caldwell MD. (1977). Vitamin requirements in patients receiving total parenteral nutrition. Arch Surg. 112 :1061-1064.
    PubMed ID: 409374
  • Cherrington AD, Caldwell MD, Dietz MR, Exton JH, Crofford OB. (1977). Effect of somatostatin on glucose uptake and production by rat tissue in vitro. Diabetes. 26 :740-748.
    PubMed ID: 195856
  • Caldwell MD, O'Neill JA, Meng HC, Stahlman MT. (1977 February). Evaluation of a new amino acid source for use in parenteral nutrition. Ann Surg. 185(2):153-161.
    PubMed ID: 402123
  • Meng HC, Stahlman MT, Otten A, Dolanski EA, Caldwell MD, O'Neill JA. (1977 May). The use of a crystalline amino acid mixture for parenteral nutrition in low-birth-weight infants. PEDIATRICS. 59(5):699-709.
    PubMed ID: 404620
  • O'Neill JA, Caldwell MD, Meng HC. (1977 May). Essential fatty acid deficiency in surgical patients. Ann Surg. 185(5):535-542.
    PubMed ID: 404973
  • Meng HC, Caldwell MD, Anderson GG, Norman JR, O'Neill JA. (1977). Essential fatty acid deficiency (EFAD) in patients on fat-free total parenteral nutrition. Fed Proc. 36 :1164.
  • Caldwell MD. (1978). Effect of altered caloried/nitrogen ratio on urea production. Fed Proc. 37 :400.
  • Caldwell MD, Lacy WW, Exton JH. (1978). Effects of adrenalectomy on amino acid and glucose metabolism of perfused rat hindlimbs. J Biol Chem. 253 :6837-6844.
    PubMed ID: 690127
  • Caldwell MD. (1979 October). Sense and solidarity (Editorial). JPEN. 3 :39.
  • O'Conner JA, Kropp JL, Hull SL, Caldwell MD. (1979). The effect of somatomedian on glucose stimulated gluconeogenesis. JPEN. 3 :22.
  • Shearer JD, Carpenter G, Peterson S, Sheldon G, Caldwell MD. (1979). Effect of intravenous nutrient supply on plasma fatty acid composition. JPEN. 3 :22.
  • Caldwell MD, Friedman HI, Lollini L, Shearer JD, Nemeth TJ. (1979). Effect of essential fatty acid deficiency (EFAD) on the induction of hepatic microsomal membrane proliferation by phenobarbital. JPEN. 3 :22.
  • Shearer JD, Caldwell MD. (1979). Effect of fasting on biochemical evidence of isolated essential fatty acid deficiency. JPEN. 3(6):501.
  • Burney DP, Goodwin CD, Caldwell MD, Amoury RA. (1979). Essential fatty acid deficiency and impaired wound healing in an infant with gastroschisis. Am Surg. 45(8):542.
    PubMed ID: 507554
  • Scott RL, Albina JE, Caldwell MD. (1979). Hypocaloric feeding: effect of carbohydrate and amino acid exchange. JPEN. 3 :20.
  • Shearer JD, Caldwell MD. (1980). Effect of IV feeding and fasting on hepatic microsomal protein and fatty acid content. JPEN. 3 :22.
  • Shearer JD, Caldwell MD, Crosby LO, Miller E, Buzby GP, Mullen JL. (1981 November). Tumor burden and gluconeogenesis. JPEN. 5
  • Caldwell MD, Kennedy-Caldwell C. (1981 June). Normal nutritional requirements. Surg Clin North Am. 61(3):489-507.
    PubMed ID: 7256510
  • O'Conner JA, Scott RL, Mellick PW, Caldwell MD. (1982 May). Perfused rat hindlimb wound model: lambda-carrageenan induced. Am J Physiol. 242(5):R570-R576.
    PubMed ID: 7081480
  • McLean GK, Rombeau JL, Caldwell MD, Ring EJ, Frieman DB. (1982 December). Transgastrostomy jejunal intubation for enteric alimentation. AJR Am J Roentgenol. 139(5):1129-1133.
    PubMed ID: 6816032
  • Friedman HI, Caldwell MD, Lollini L, Shearer JD, Nemeth TJ. (1982 January). Effects of essential fatty acid deficiency on the induction of liver microsomal membranes by phenobarbital: an ultrastructural and biochemical investigation. J Parenter Enteral Nutr. 6(1):12-19.
    PubMed ID: 7200537
  • Scott RL, Albina JE, Caldwell MD. (1982 November). Effects of hypocaloric dextrose and amino acids on body composition and nitrogen balance in rats. J Parenter Enteral Nutr. 6(6):489-495.
    PubMed ID: 6820073
  • Rombeau JL, Twomey PL, McLean GK, Forlaw L, Del Rio D, Caldwell MD. (1983 April). Experience with a new gastrostomy-jejunal feeding tube. SURGERY. 93(4):574-578.
    PubMed ID: 6403996
  • Shearer JD, Caldwell MD, Crosby LO, Miller E, Buzby GP, Mullen JL. (1983 April). Tumor effects on gluconeogenesis in the isolated perfused rat liver. JPEN. 7(2):105-109.
    PubMed ID: 6682907
  • Thompson WR, Amaral JF, Caldwell MD, Martin HF, Randall HT. (1983 November). Complications and weight loss in 150 consecutive gastric exclusion patients. Am J Surg. 146(5):602-612.
    PubMed ID: 6638265
  • Shearer JD, Morris AS, Albina JE, Caldwell MD. (1984 April). Effect of starvation on the local and systemic metabolic effects of the lambda-carrageenan wound. Am J Surg. 147(4):456-462.
    PubMed ID: 6711747
  • Caldwell MD, Shearer JD, Morris AS, Mastrofrancesco B, Henry WL, Albina JE. (1984 July). Evidence for aerobic glycolysis in lambda-carrageenan-wounded skeletal muscle. J Surg Res. 37(1):63-68.
    PubMed ID: 6738047
  • Shearer JD, Buzby GP, Mullen JL, Miller E, Caldwell MD. (1984 October). Alteration in pyruvate metabolism in the liver of tumor-bearing rats. Cancer Res. 44(10):4443-4446.
    PubMed ID: 6467203
  • Amaral JF, Thompson WR, Caldwell MD, Martin HF, Randall HT. (1984 April). Prospective metabolic evaluation of 150 consecutive patients who underwent gastric exclusion. Am J Surg. 147(4):468-476.
    PubMed ID: 6711748
  • Amaral JF, Caldwell MD, Gann DS. (1984). The effects of naloxone on glucose metabolism in skeletal muscle. Surg Forum. 35 :52-55.
  • Shearer JD, Miller E, Buzby GP, Mullen JL, Caldwell MD. (1984). Altered substrate utilization in the liver of the tumor-bearing host. JPEN. 8(1):90.
  • Henry WL, Shearer JD, Mastrofrancesco B, Albina JE, Morris AS, Caldwell MD. (1984). Can starvation expain systemic effects of wounding. JPEN. 8(1):92.
  • Morris AS, Caldwell MD, Shearer JD, Albina JE. (1984). Evaluation of aerobic glycolysis in wounded tissue. JPEN. 8(1):90.
  • Shearer JD, Mastrofrancesco B, Henry WL, Albina JE, Morris AS, Caldwell MD. (1984). Oxidative capacity of lambda-carrageenan wounded skeletal muscle. Fed Proc. 43(3):412.
  • Morris AS, Mastrofrancesco B, Albina JE, Shearer JD, Caldwell MD. (1984). An explanation for the proposed energy deficit of wounded tissue. J Trauma. 24(7):1.
  • Shearer JD, Amaral JF, Mastrofrancesco B, Albina JE, Morris AS, Caldwell MD. (1984). The effect of adrenalectomy on lambda-carrageenan wounded skeletal muscle. Circ Shock. 13 :65-66.
  • Albina JE, Shearer JD, Mastrofrancesco B, Morris AS, Henry WL, Caldwell MD. (1984). Amino acid release from perfused rat hindlimbs: effects of injury and semistarvation. J Trauma. 24(7)
  • Amaral JF, Caldwell MD, Gann DS. (1984). The effect of naloxone and beta endorphin on glucose metabolism in skeletal muscle. J Trauma. 24(7)
  • Albina JE, Shearer JD, Mastrofrancesco B, King P, Goldstein L, Caldwell MD. (1985). Glutmine (GLN) metabolism in the lambda-carrageenan muscle wound. Fed Proc. 44 :1213.
  • Morris AS, Henry WL, Shearer JD, Caldwell MD. (1985 August). Macrophage interaction with skeletal muscle. A potential role of macrophages in determining the energy state of healing wounds. J Trauma. 25(8):751-757.
    PubMed ID: 4020909
  • Morris AS, Shearer JD, Henry WL, Mastrofrancesco B, Caldwell MD. (1985 April). A macrophage-mediated factor that increases the high energy phosphate content of skeletal muscle. J Surg Res. 38(4):373-382.
    PubMed ID: 3999732
  • Gartner MH, Caldwell MD. (1985 December). Nutrition and molecular biology. Clinical Nutrition II: Parental Nutrition. 2nd :203-208.
  • Amaral JF, Thompson WR, Caldwell MD, Martin HF, Randall HT. (1985 February). Prospective hematologic evaluation of gastric exclusion surgery for morbid obesity. Ann Surg. 201(2):186-193.
    PubMed ID: 3970598
  • Morris AS, Shearer JD, Caldwell MD. (1985). The role of cellular infiltrate on glucose metabolism in wounded tissue. Surg Forum. 36 :95-97.
  • Morris AS, Shearer JD, Caldwell MD, Mastrofrancesco B. (1985). Comparative study of the metabolic response to injury. JPEN. 9(1):114.
  • Shearer JD, Amaral JF, Hrbek C, Mastrofrancesco B, Caldwell MD. (1985). Hepatic gluconeogenesis from lactate following injury. JPEN. 10(1):Suppl 9.
  • Amaral JF, Mendes C, Caldwell MD, Gann DS. (1985). Beta-endorphin does not alter glucose metabolism in skeletal muscle. Circ Shock. 16(1):78.
  • Shearer JD, Morris AS, Caldwell MD. (1985). Control phosphofructokinase activity in lambda-carrageenan wounded muscle. Fed Proc. 44 :1.
  • Albina JE, Shearer JD, Mastrofrancesco B, Caldwell MD. (1986 January). Amino acid metabolism after lambda-carrageenan injury to rat skeletal muscle. Am J Physiol. 250(1 Pt 1):E24-E30.
    PubMed ID: 3942210
  • Morris AS, Shearer JD, Forster J, Mastrofrancesco B, Henry WL, Caldwell MD. (1986 October). The relationship of purine metabolism to the macrophage-mediated increase of high energy phosphates in skeletal muscle. J Surg Res. 41(4):339-346.
    PubMed ID: 3773494
  • Amaral JF, Shearer JD, Mastrofrancesco B, Gann DS, Caldwell MD. (1986). Can lactate serve as a fuel for wounded tissue? SURGERY. 100(2):252-261.
    PubMed ID: 3738754
  • Amaral JF, Shearer JD, Mastrofrancesco B, Caldwell MD. (1986). Hepatic metabolism following injury and adrenalectomy. Circ Shock. 18(4):375.
  • Amaral JF, Shearer JD, Caldwell MD. (1986). Insulin-like activity of macrophages on glucose metabolism in skeletal muscle. Circ Shock. 18(4):343.
  • Amaral JF, Shearer JD, Mastrofrancesco B, Caldwell MD. (1986). The effect of external glucose supply in wounded and non-wounded tissue. Fed Proc. 45(4):1014.
  • Shearer JD, Hrbek C, Caldwell MD. (1986). Phosphofructokinase(PFK) activity correlates with the cellular infiltrate in wounded rat skeletal muscle. Fed Proc. 45(3):701.
  • Mastrofrancesco B, Shearer JD, Hrbek C, Forster J, Caldwell MD. (1986). High energy phosphate (HEP) content in wounded rat skeletal muscle: a time study. Fed Proc. 45(3):701.
  • Platoniotis G, Shearer JD, Hrbek C, Caldwell MD. (1986). Effects of wounding on circulating concentrations of ketone bodies. Fed Proc. 45(3):701.
  • Amaral JF, Shearer JD, Caldwell MD. (1986). Examination of lactate metabolism in the cellular infiltrate of wounded tissue. Surg Forum. 37 :30-33.
  • Albina JE, King P, Ahmad R, Henry WL, Goldstein JL, Caldwell MD. (1986). Intracellular glutamine (ICGLN) and glutamine synthesis activity (GSA) in wounded rat skeletal muscle. Fed Proc. 45(3):546.
  • Albina JE, Henry WL, Ahmad R, Caldwell MD. (1986). Glutamine metabolism in the healing wound. JPEN. 10(1):Suppl 10.
  • Shearer JD, Daley JM, Platoniotis G, Caldwell MD. (1987). Substrate supply is the determinant of increased hepatic gluconeogenesis following injury. Fed Proc. 46(3):326.
  • Daley JM, Shearer JD, Caldwell MD. (1987). Does wounded tissue regulate hepatic glucose production? Surg Forum. 38 :23-25.
  • Albina JE, Henry WL, King PA, Shearer JD, Mastrofrancesco B, Goldstein L, Caldwell MD. (1987 January). Glutamine metabolism in rat skeletal muscle wounded with lambda-carrageenan. Am J Physiol. 252(1 Pt 1):E49-E56.
    PubMed ID: 2880509
  • Daley JM, Shearer JD, Mastrofrancesco B, Caldwell MD. (1987). A longitudinal study of glucose uptake and lactate production in lambda-carrageenan wounded tissue. Fed Proc. 46(30):326.
  • Pomp A, Caldwell MD, Feitelson m, Varella L, Albina JE, Seldinger. (1987). Technique for central venous catheter insertions. Clin Nut. 6 :103.
  • Albina JE, Henry WL, Barbul A, Mastrofrancesco B, Caldwell MD. (1987). Arginine metabolism in wounded tissue. Clin Nut. 6 :64.
  • Caldwell MD, Shearer JD, Forster J, Amaral JF, Bowen W, Mastrofrancesco B. (1987). Is the cellular infiltrate responsible for the increased glucose uptake of wounded tissue. Clin Nut. 6 :47.
  • Forster J, Shearer JD, Mastrofrancesco B, Caldwell MD. (1987). Determinants of the rate of glycolysis in wounded skeletal muscle. Fed Proc. 46(3):412.
  • Mastrofrancesco B, Amaral JF, Caldwell MD. (1987). Substrate concentration in interstitial fluid from wounds. Fed Proc. 46(30):982.
  • Albina JE, Henry WL, Amaral JF, Shearer JD, Caldwell MD. (1987). Arginase activity in wounds. Fed Proc. 46(40):1086.
  • Daley JM, Engeland WC, Graeber T, Miller P, Shearer JD, Gann DS, Caldwell MD. (1988 December). Wounded hindlimbs release substances with ACTH-like immunoreactivity. Br J Surg. 75(12)
  • Shearer JD, Amaral JF, Caldwell MD. (1988 July). Glucose metabolism of injured skeletal muscle: the contribution of inflammatory cells. Circ Shock. 25(3):131-138.
    PubMed ID: 3168170
  • Amaral JF, Shearer JD, Mastrofrancesco B, Gann DS, Caldwell MD. (1988 September). The temporal characteristics of the metabolic and endocrine response to injury. J Trauma. 28(9):1335-1352.
    PubMed ID: 2843656
  • Albina JE, Mills CD, Barbul A, Thirkill CE, Henry WL, Mastrofrancesco B, Caldwell MD. (1988 April). Arginine metabolism in wounds. Am J Physiol. 254(4 Pt 1):E459-E467.
    PubMed ID: 3354662
  • Zimbler A, Caldwell MD, Mills CD. (1988). The effects of diabetic rat wound fluid on fibroblast growth. Surg Forum. 39 :629-632.
  • Pomp A, Caldwell MD. (1988). Catheter-related sepsis 1. Reducing the infection rate from triple-lumen catheters. J of Critical Illness. 3(6):16-21.
  • Wyshock E, Caldwell MD, Crowley JP. (1988 November). Deep venous thrombosis, inflammatory bowel disease and protein S deficiency. Am J Clin Pathol. 90(5):633-635.
    PubMed ID: 2972196
  • Caldwell MD. (1988). Carbohydrate and energy metabolism in healing wounds. Prog Clin Biol Res. 266 :183-213.
    PubMed ID: 3289042
  • Shearer JD, Forster J, Leith J, Vezeridis M, Caldwell MD. (1988). Effect of irradiation and the role of t-lymphocytes on L-carraggeenan induced inflammation. FASEB J. 2 :A1179.
  • Barbul A, Caldwell MD, Pines E, Hunt E. (1988). Growth factors and other aspects of wound healing: biological and clinical implications. Proceedings of the Second International Symposium on Tissue Repair. Tarpon Springs, Florida, May 13-17, 1987. Prog Clin Biol Res. 266 :1-342.
    PubMed ID: 3380845
  • Falcon A, Shearer JD, Caldwell MD. (1988). The effects of topical fibronectin on polyvinyl alcohol sponge implants. FASEB J. 2 :A1111.
  • Bereiter DF, Shearer JD, Caldwell MD. (1988). A new technique for isolating cells from a wounded tissue. FASEB J. 2 :A903.
  • Mills CD, Caldwell MD, Gann DS. (1988). Evidence of a transient "window" of immunodeficiency early following trauma. FASEB J. 2 :A903.
  • Albina JE, Mills CD, Henry WL, Caldwell MD. (1989 December). Regulation of macrophage physiology by L-arginine: role of the oxidative L-arginine deiminase pathway. J Immunol. 143(11):3641-3646.
    PubMed ID: 2584712
  • Amaral JF, Shearer JD, Mastrofrancesco B, Gann DS, Caldwell MD. (1989). High dose endotoxin inhibits glucose uptake in skeletal muscle. Arch Surg. 124 :727-732.
  • Amaral JF, O'Conner JA, Shearer JD, Hull SL, Caldwell MD. (1989 June). Somatomedian-A inhibits glucagon-stimulated hepatic gluconeogenesis. J Trauma. 29(6):842-846.
    PubMed ID: 2738982
  • Daley JM, Engeland WC, Graeber T, Shearer JD, Caldwell MD. (1989). Release of immunoreactive ACTH and b-endorphin from injured tissue. FASEB J. 3 :A854.
  • Bereiter DF, Shearer JD, Caldwell MD. (1989). Contribution of individual cellular components to glucose metabolism in wounded tissue. FASEB J. 3 :A909.
  • Mastrofrancesco B, Pricolo VE, Caldwell MD. (1989). The effect of streptozotocin diabetes on wound fluid proline precursers content. FASEB J. 3 :A929.
  • Pricolo VE, Mastrofrancesco B, Caldwell MD. (1989). Early stimulatory and late inhibitory effects of wound fluid on fibroblast growth. FASEB J. 3 :A1212.
  • Shearer JD, Bereiter DF, Mastrofrancesco B, Caldwell MD. (1989). Inflammatory cells release a factor(s) which increases proteolysis in skeletal muscle. FASEB J. 3 :A909.
  • Albina JE, Caldwell MD, Henry WL, Mills CD. (1989 March). Regulation of macrophage functions by L-arginine. J Exp Med. 169(3):1021-1029.
    PubMed ID: 2538541
  • Caldwell MD. (1989 August). Local glutamine metabolism in wounds and inflammation. Metabolism. 38(8 Suppl 1):34-39.
    PubMed ID: 2668702
  • Forster J, Morris AS, Shearer JD, Mastrofrancesco B, Inman KC, Caldwell MD. (1989 June). Glucose uptake and flux through phosphofructokinase in wounded rat skeletal muscle. Am J Physiol. 256(6 Pt 1):E788-E797.
    PubMed ID: 2525343
  • Mills CD, Caldwell MD, Gann DS. (1989 March). Evidence of a plasma-mediated "window" of immunodeficiency in rats following trauma. J Clin Immunol. 9(2):139-150.
    PubMed ID: 2785530
  • Winkler MF, Pomp A, Caldwell MD, Albina JE. (1989 July). Transitional feeding: the relationship between nutritional intake and plasma protein concentrations. J Am Diet Assoc. 89(7):969-970.
    PubMed ID: 2501377
  • Pomp A, Caldwell MD, Albina JE. (1989 October). Subcutaneous infusion ports for administration of parenteral nutrition at home. Surg Gynecol Obstet. 169(4):329-333.
    PubMed ID: 2506656
  • Shearer JD, Bereiter DF, Mastrofrancesco B, Caldwell MD. (1990). Lymphocyte substrate utilization in the local wound environment. FASEB J. 4 :A639.
  • Pueschel SM, Hillemeier C, Caldwell MD, Senft K, Mevs C, Pezzullo JC. (1990 June). Vitamin A gastrointestinal absorption in persons with Down's syndrome. J Ment Defic Res. 34(3):269-275.
    PubMed ID: 2143232
  • Falcone PA, Caldwell MD. (1990). Wound metabolism. Clinics in Plastic Surg. 17 :443-456.
    PubMed ID: 2199136
  • Daley JM, Shearer JD, Mastrofrancesco B, Caldwell MD. (1990 February). Glucose metabolism in injured tissue: a longitudinal study. SURGERY. 107(2):187-192.
    PubMed ID: 2405537
  • Albina JE, Mills CD, Henry WL, Caldwell MD. (1990 May). Temporal expression of different pathways of L-arginine metabolism in healing wounds. J Immunol. 144(10):3877-3880.
    PubMed ID: 2332635
  • Caldwell MD. (1990 December). Topical wound therapy. An historical perspective. J Trauma. 30(Suppl 12):S116-S1122.
    PubMed ID: 2254970
  • Pricolo VE, Caldwell MD, Mastrofrancesco B, Mills CD. (1990 June). Modulatory activities of wound fluid on fibroblast proliferation and collagen synthesis. J Surg Res. 48(6):534-538.
    PubMed ID: 2362413
  • Shearer JD, Bereiter DF, Mastrofrancesco B, Caldwell MD. (1991). Wound fluid enhancement of essential amino acid uptake by wound deprived fibroblasts. FASEB J. 5 :542.
  • Mills CD, Caldwell MD. (1991). Molecular basis of "suppressor" macrophages. FASEB J. 5 :542.
  • Gartner MH, Benson JD, Caldwell MD. (1991). Time course of epidermal growth factor mRNA expression in healing wounds using polymerase chain reaction. Surg Forum. 42 :643-645.
  • Gartner MH, Shearer JD, Bereiter DF, Mills CD, Caldwell MD. (1991 August). Wound fluid amino acid concentrations regulate the effect of epidermal growth factor on fibroblast replication. SURGERY. 110(2):448-455.
    PubMed ID: 1858053
  • Caldwell MD, Mastrofrancesco B, Shearer JD, Bereiter DF. (1991). The temporal change in amino acid concentration within wound fluid--a putative rationale. Prog Clin Biol Res. 365 :205-222.
  • Mills CD, Pricolo VE, Albina JE, Caldwell MD. (1991). Concomitant macrophage activation and fibroblast/lymphocyte inhibition by wound fluid: the "arginine-deficiency of inflammation" is a partial explanation. Prog Clin Biol Res. 365 :193-203.
    PubMed ID: 1862132
  • Shearer JD, Mills CD, Caldwell MD. (1992). Differential regulation of macrophage argine metabolism. FASEB J. 6(5):A1719.
  • Millar CJ, Caldwell MD, Shearer JD. (1992). Metabolism of arginine to nitric oxide can inhibit both cancer and anti-cancer lymphocyte: ornithine may stimulate both. FASEB J. 6(5):A1712.
  • Gartner MH, Benson J, Caldwell MD. (1992 April). Insulin-like growth factors I and II expression in the healing wound. J Surg Res. 52(4):389-394.
    PubMed ID: 1350650
  • Mills CD, Shearer JD, Evans RT, Caldwell MD. (1992 October). Macrophage arginine metabolism and the inhibition or stimulation of cancer. J Immunol. 149(8):2709-2714.
    PubMed ID: 1401910
  • Gartner MH, Aberle LA, Richards JR, Caldwell MD. (1992). Interrelationship between growth factor messenger RNA and protein product in the healing wound. Surg Forum. 43 :683-685.
  • Ulland AE, Gartner MH, Richards JR, Caldwell MD, Shearer JD. (1993). Characterization of wound derived insulin. Wound Repair and Regeneration. 1(2):130.
  • Ulland AE, Gartner MH, Caldwell MD. (1993). Vitamin A reduced plasma corticosterone levels. A putative explanation for the beneficial effects of vitamin A on steroid-impaired wound healing. Surg Forum. 44 :686-689.
  • Cipolle M, Pasquale M, Cerra FB, Caldwell MD, Shearer JD. (1994 July). Blunt injury augments IL-6, but not TNF, in the isolated perfused rat hindlimb. J Trauma. 37(1):91-98.
    PubMed ID: 8028066
  • Shearer JD, Caldwell MD. (1994). Altered arginine metabolism in diabetic wounds. Wound Repair and Regeneration. 2(1):91.
  • Lum CT, Caldwell MD, Sicard R, Sutherland DER, Penner B. (1994). Preliminary studies of rat pancreas duct epitheal cells in an acute inflammatory wound healing model. Transplant Proceedings. 26(6):3469-3470.
    PubMed ID: 7998229
  • Ulland AE, Gartner MH, Richards JR, Caldwell MD. (1994). Retinoic acid restores transforming growth factor-B1 concentrations in a steroid-impaired wound healing model. Surg Forum. 45 :714-716.
  • Arlein WJ, Shearer JD, Caldwell MD. (1995). Investigation of rat fibroblast replication using PKE-2, a fluorescent label. Wound Repair and Regeneration. 3 :81.
  • Santilli SM, Stevens RB, Anderson JG, Payne WD, Caldwell MD. (1995). Transarterial wall oxygen gradients at the dog carotid bifuracation. Am J Physiol (Heart Circ Physiol 37). 268 :H155-H161.
    PubMed ID: 7840259
  • Santilli SM, Stevens RB, Anderson JG, Caldwell MD. (1995). The effect of aging on the transarterial wall oxygen gradient. Annals of Vasc Surg. 9(2):146-151.
    PubMed ID: 7786699
  • Arlein WJ, Shearer JD, Caldwell MD. (1995). Identification of macrophage growth factor in wound fluid. Surg Forum. 46 :748-751.
  • Shearer JD, Aberle LA, Richards JR, Caldwell MD. (1995). Flow cytometric analysis of wound cell replication using PKE-2. Wound Repair and Regeneration. 3 :101.
  • Ulland AE, Shearer JD, Caldwell MD. (1995). Retinoic acid reverses steroid impaired arginase activity in rat wounds. Wound Repair and Regeneration. 3 :104.
  • Wotus C, Shearer JD, Caldwell MD. (1996). Stimulatory and inhibitory effects of wound fluid (WF) on fibroblast proliferation. FASEB J. 10 :A774.
  • Shearer JD, Coulter CF, Caldwell MD. (1996). Differential degradation of peptide hormones and growth factors in wounds. FASEB J. 10 :A775.
  • Coulter CF, Shearer JD, Caldwell MD. (1996). Characterization of insulin degrading activity in normal healing wounds. FASEB J. 10 :A775.
  • Shearer JD, Coulter CF, Caldwell MD. (1996). Insulin degrading activity in normal diabetic and insulin-treated diabetic rats. Wound Repair and Regeneration. 4(1):A174.
  • Shearer JD, Richards JR, Mills CD, Caldwell MD. (1997 February). Differential regulation of macrophage arginine metabolism: a proposed role in wound healing. Am J Physiol. 272(2 Pt 1):E181-E190.
    PubMed ID: 9124321
  • Bjarnason H, Kruse JR, Asinger DA, Nazarian GK, Dietz CA, Caldwell MD,...Hunter DW. (1997 May). Iliofemoral deep venous thrombosis: safety and efficacy outcome during 5 years of catheter-directed thrombolytic therapy. J Vasc Interv Radiol. 8(3):405-418.
    PubMed ID: 9152914
  • Ulland AE, Shearer JD, Coulter CF, Caldwell MD. (1997 June). Altered wound arginine metabolism by corticosterone and retinoic acid. J Surg Res. 70(1):84-88.
    PubMed ID: 9228933
  • Shearer JD, Coulter CF, Engeland WC, Roth RA, Caldwell MD. (1997 October). Insulin is degraded extracellularly in wounds by insulin-degrading enzyme (EC 3.4.24.56). Am J Physiol. 273(4 Pt 1):E657-E664.
    PubMed ID: 9357792
  • Lunzer MM, Hotvedt PS, Dietz CA, Caldwell MD. (1997). Limb venous hemodynamic function. Relative reproducibility of standard tip-toe exercise and treadmill walking exercise techniques. JI of Vasc Techn. 21(1):31-38.
  • Coulter CF, Shearer JD, Caldwell MD. (1997). An absence of wound insulin degradation parallels impaired wound healing in CM-INH-treated, steroid-treated and diabetic rats. J of Minn Acad Sci. 61 :6.
  • Tsolakis IA, Walvatne C, Caldwell MD. (1998 March). Cystic adventitial disease of the popliteal artery: diagnosis and treatment. Eur J Vasc Endovasc Surg. 15(3):188-194.
    PubMed ID: 9587330
  • Arlein WJ, Shearer JD, Caldwell MD. (1998 October). Continuity between wound macrophage and fibroblast phenotype: analysis of wound fibroblast phagocytosis. Am J Physiol.. 275(4 Pt 2):R1041-R1048.
    PubMed ID: 9756532
  • Shearer JD, Glanzer T, Coulter CF, Caldwell MD. (1998). Differential degradation of insulin and insulin-like growth factor 1 in wound fluid. FASEB J. 12 :A146.
  • Earll MD, Wayne J, Caldwell MD, Adelaar R. (1998 July). Comparison of two proximal osteotomies for the treatment of hallux valgus. Foot Ankle Int. 19(7):425-429.
    PubMed ID: 9694119
  • Holtzman J, Caldwell MD, Walvatne C, Kane R. (1999 March). Long-term functional status and quality of life after lower extremity revascularization. J Vasc Surg. 29(3):395-402.
    PubMed ID: 10069902
  • Bromberek BA, Enever PA, Shreiber DI, Caldwell MD, Tranquillo RT. (2002 May). Macrophages influence a competition of contact guidance and chemotaxis for fibroblast alignment in a fibrin gel coculture assay. Exp Cell Res. 275(2):230-242.
    PubMed ID: 11969292
  • Weber WW, Caldwell MD, Kurth H. (2003). Edging toward personalized medicine. Curr Pharmacogenomics. 1 :193-202.
  • Hillman MA, Wilke RA, Caldwell MD, Berg RL, Glurich IE, Burmester JK. (2004 August). Relative impact of covariates in prescribing warfarin according to CYP2C9 genotype. Pharmacogenetics. 14(8):539-547.
    PubMed ID: 15284536
  • McCarty CA, Wilke RA, Giampietro PF, Wesbrook SD, Caldwell MD. (2005 March). Marshfield Clinic Personalized Medicine Research Project (PMRP): design, methods and recruitment for a large population-based biobank. Personalized Medicine. 2(1):49-79.
  • Wilke RA, Berg RL, Vidaillet HJ, Caldwell MD, Burmester JK, Hillman MA. (2005 November). Impact of age, CYP2C9 genotype, and concomitant medication on the rate of rise for prothrombin time during the first 30 days of warfarin therapy. Clin Med Res. 3(4):207-213.
    PubMed ID: 16303885
  • Hillman MA, Wilke RA, Yale SH, Vidaillet HJ, Caldwell MD, Glurich IE,...Burmester JK [including Berg RL, Schmelzer JR.] (2005 August). A prospective, randomized pilot trial of model-based warfarin dose initiation using CYP2C9 genotype and clinical data. Clin Med Res. 3(3):137-145.
    PubMed ID: 16160068
  • Luikart SD, Levay-Young B, Hinkel T, Shearer J, Mills C, Caldwell MD,...Oegema TR.. (2006). Mactinin treatment promotes wound-healing-associated inflammation in urokinase knockout mice. Wound Rep Reg. 14 :123-128.
  • Caldwell MD, Berg RL, Zhang KQi, Glurich IE, Schmelzer JR, Yale SH,...Burmester JK [including Vidaillet HJ.] (2007 March). Evaluation of genetic factors for warfarin dose prediction. Clin Med Res. 5(1):8-16.
    PubMed ID: 17456829
  • Morgan W, Caldwell MD, Brady JM, Stemper ME, Reed KD, Shukla SK. (2007 February). Necrotizing fasciitis due to a methicillin-sensitive Staphylococcus aureus harboring an enterotoxin gene cluster. J Clin Microbiol. 45(2):668-671.
    PubMed ID: 17166962
  • McCarty CA, Peissig PL, Caldwell MD, Wilke RA. (2008 September). The Marshfield Clinic Personalized Medicine Research Project: 2008 scientific update and lessons learned in the first 6 years. Personalized Medicine. 5(5):529-542.
  • Caldwell MD, Awad T, Johnson JA, Gage BF, Falkowski M, Gardina P,...Burmester JK [including Schmelzer JR, Glurich IE, Vidaillet HJ, Yale SH, Zhang KQi, Berg RL.] (2008 April). CYP4F2 genetic variant alters required warfarin dose. BLOOD. 111(8):4106-12.
    PubMed ID: 18250228
  • Schmelzer JR, Berg RL, Burmester JK, Yale SH, Caldwell MD. (2009 March). Is cost-effective genotype-informed warfarin dosing closer than we think? Ann Intern Med. [www.annals.org]
  • Hogan KJ, Burmester JK, Caldwell MD, Hogan QH, Coursin DB, Green DN,...Domanico MJ. (2009 September). Perioperative genomic profiles using structure-specific oligonucleotide probes. Clinical Medicine & Research. 7(3):69-84.
    PubMed ID: 19474452
  • International Warfarin Pharmacogenetics Consortium,, Klein TE, Altman RB, Eriksson N, Gage BF, Kimmel SE,...Burmester JK [including Caldwell MD, Berg RL.] (2009 February). Estimation of the warfarin dose with clinical and pharmacogenetic data. NEW ENGLAND JOURNAL OF MEDICINE. 360(8):753-64.
    PubMed ID: 19228618
  • Lenzini P, Wadelius M, Kimmel S, Anderson JL, Jorgensen AL, Pirmohamed M,...Gage BF [including Caldwell MD, Dowd MB, Berg RL.] (2010 May). Integration of Genetic, Clinical, and INR Data to Refine Warfarin Dosing. Clin Pharmacol Ther. 87(5):572-8.
    PubMed ID: 20375999
  • Glurich IE, Burmester JK, Caldwell MD. (2010 May). Understanding the pharmacogenetic approach to warfarin dosing. HEART FAILURE REVIEWS. 13(3):239-48.
    PubMed ID: 18998206
  • Caldwell MD. (2010 December). Wounds and wound management. Preface. Surgical Clinics of North America. 90(6):xiii.
    PubMed ID: 21074030
  • Burmester JK, Berg RL, Yale SH, Rottscheit CM, Glurich IE, Schmelzer JR, Caldwell MD. (2011 June). A randomized controlled trial of genotype-based Coumadin initiation. Genet Med. 13(6):509-18.
    PubMed ID: 21423021
  • Burmester JK, Berg RL, Glurich IE, Yale SH, Schmelzer JR, Caldwell MD. (2011 November). Absence of novel CYP4F2 and VKORC1 coding region DNA variants in patients requiring high warfarin doses. Clinical Medicine & Research. 9(3-4):119-24.
    PubMed ID: 21562135
  • Page D, Costa V, Natarajan S, Barnard A, Peissig PL, Caldwell MD. (2012). Identifying Adverse Drug Events by Relational Learning Association for the Advancement of Artificial Intelligence. :15999-1605.
  • Davis J, Costa V, Peissig PL, Caldwell MD, Berg E, Page D. (2012). Demand-Driven Clustering in Relational Domains for Predicting Adverse Drug Events Proceedings of the 29th International Conference on Machine Learning.
  • Anderson ER, Burmester JK, Caldwell MD. (2012 August). Evaluation of a Mitochondrial DNA Mutation in Maternally Inherited and Sporadic Cases of Dupuytren’s Disease. Clinical Medicine & Research. 10(3):122-6.
    PubMed ID: 22634541
  • Horne BD, Lenzini P, Wadelius M, Jorgensen AL, Kimmel SE, Ridker PM,...Gage BF [including Burmester JK, Caldwell MD.] (2012 February). Pharmacogenetic warfarin dose refinements remain significantly influenced by genetic factors after one week of therapy. THROMBOSIS AND HAEMOSTASIS. 107(2):232-40.
    PubMed ID: 22186998
  • Davis JG, Santos Costa V, Peissig PL, Caldwell MD, Page D. (2013 January). A preliminary investigation into predictive models for adverse drug events. Expanding the Boundaries of Health Informations Using Artificial Intelligence: Papers from the AAAI . :8-11.
  • Kimmel SE, French B, Anderson JL, Gage BF, Johnson JA, Rosenberg Y,...Ellenberg J [including Caldwell MD.] (2013 September). Rationale and design of the Clarification of Optimal Anticoagulation through Genetics trial. AMERICAN HEART JOURNAL. 166(3):435-41.
    PubMed ID: 24016491
  • Peissig PL, Santos Costa V, Caldwell MD, Rottscheit CM, Berg RL, Mendonca EA, Page D. (2014 December). Relational machine learning for electronic health record-driven phenotyping. J Biomed Inform. 52 :260-70.
    PubMed ID: 25048351
  • Anderson ER, Ye Z, Caldwell MD, Burmester JK. (2014 December). SNPs Previously Associated with Dupuytren's Disease Replicated in a North American Cohort. Clinical Medicine & Research. 12(3-4):133-7.
    PubMed ID: 24573701